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Do not use hydrochlorothiazide and losartan if you are pregnantStop using this medication and tell your doctor right away if you become pregnant.

You may have very low blood pressure while using HyzaarTell your doctor if you experience persistent or severe weaknessvomitingdiarrheaor sweating.

If you have diabetes or kidney diseaseyou may not be able to take Hyzaar along with any medicine that contains aliskirensuch as AmturnideTekturnaTekamloor Valturna.

Use of drugs that act on the renin-angiotensin system during the second and third trimesters of pregnancy reduces renal function and increases fetal and neonatal morbidity and deathResulting oligohydramnios can be associated with fetal lung hypoplasia and skeletal deformationsPotential neonatal adverse effects include skull hypoplasiaanuriahypotensionrenal failureand deathWhen pregnancy is detecteddiscontinue HYZAAR as soon as possibleThese adverse outcomes are usually associated with the use of these drugs in the second and third trimester of pregnancyMost epidemiologic studies examining fetal abnormalities after exposure to antihypertensive use in the first trimester have not distinguished drugs affecting the renin-angiotensin system from other antihypertensive agentsAppropriate management of maternal hypertension during pregnancy is important to optimize outcomes for both mother and fetus.

Hyzaar is the brand name of a combination medicine that contains the drugs losartan and hydrochlorothiazide.

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