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In addition to reporting episodes of bleeding and easy bruisingpatients should be warned to promptly report any other signs which might also suggest the early development of blood dyscrasia such as pyrexia and sore throatA full blood count should be performed if infection is suspected or there is any other clinical evidence of blood dyscrasiaCilostazol should be discontinued promptly if there is clinical or laboratory evidence of haematological abnormalities.

Cilostazol affects both vascular beds and cardiovascular functionIt produces heterogeneous dilation of vascular bedswith greater dilation in femoral beds than in vertebralcarotid or superior mesenteric arteriesRenal arteries were not responsive to the effects of cilostazol.

Based on AUCoverall pharmacological activity of cilostazol increases 19when co-administered with diltiazemBased on these datano dose adjustment is necessary.

Cilostazol is used to improve the symptoms of a certain blood flow problem in the legsintermittent claudicationCilostazol can decrease the muscle pain/cramps that occur during exercise/walkingClaudication pain is caused by too little oxygen getting to the musclesCilostazol can increase blood flow and the amount of oxygen that gets to the muscles.

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