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As documented with other antibiotics when used in patients with difficult to treat infections and/or for prolonged periodsemergent decreases in susceptibility have been observed with linezolidResistance to linezolid has been reported in enterococciStaphylococcus aureus and coagulase negative staphylococciThis generally has been associated with prolonged courses of therapy and the presence of prosthetic materials or undrained abscessesWhen antibiotic-resistant organisms are encountered in the hospital it is important to emphasize infection control policies.

During your treatment with Zyvoxdo not start or stop using any other medications unless your doctor tells you toYou should not use this medicine at is resistant to medication if you have untreated or uncontrolled high blood pressurea carcinoid tumoradrenal gland tumoror a severely overactive thyroidIf you take an antidepressant or psychiatric medicationcall your doctor right away if you have signs of a serious drug interactionincludingconfusionmemory problemsfeeling hyperactivementally or physicallyloss of coordinationmuscle twitchingshiveringsweatingdiarrheaand/or fever.

The dose recommendation for the solution for infusion and the tablets/granules for oral suspension are identical and are as follows:

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tricyclic antidepressants , including doxepin, should not be taken with any of the monoamine oxidase inhibitor maoi class of antidepressants for example, isocarboxazid marplan , phenelzine nardil , tranylcypromine parnate , selegiline eldepryl , and procarbazine matulane or other drugs that inhibit monoamine oxidase such as linezolid zyvox and intravenous methylene blue.

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